The Mushroom that Benefits Blood Sugar, Cholesterol, Immunity & More (2024)

The Mushroom that Benefits Blood Sugar, Cholesterol, Immunity & More (1)

Medicinal mushrooms have been used for thousands of years to help promote better health, and mushroom varieties, such as psilocybin mushrooms and turkey tail mushrooms, are well-known for their incredible health-promoting properties. The maitake mushroom is no exception.

Not only is it delicious and full of nutrients, but it also boasts some pretty amazing health benefits.

In recent years, the maitake mushroom has garnered worldwide attention as more and more emerging research continues to unearth its multitude of health-promoting properties. This is largely thanks to the presence of D-fraction, a specific compound extracted from the maitake mushroom that has been shown to have therapeutic effects for cancer patients.

Today, maitake mushrooms are continuing to gain widespread popularity across the globe as more people have come to appreciate them for their medicinal properties, versatility and delicious flavor.

What Are Maitake Mushrooms?

Also known ashen of the woods orGrifola frondosa, maitake mushrooms are a type of edible fungi that are native to China but are also grown in Japan and North America. They are commonly found in clusters at the base of maple, oak or elm trees and can grow to over 100 pounds, earning them the title “king of the mushrooms.”

The maitake mushroom has a long history in its use as both a culinary and medicinal mushroom. The name “maitake” comes from its Japanese name, which translates to “dancing mushroom.” It is said that people would dance for joy upon discovering the mushroom thanks to its potent healing powers.

This beneficial food has a unique, frilly appearance, a delicate texture and an earthy flavor that works well in many different dishes, from burgers to stir-fries and beyond. While often considered a staple in Japanese cuisine (like oyster mushrooms and shiitake mushrooms), Grifola frondosa has also been gaining widespread popularity around the globe in recent years.

Not only that, but these medicinal mushrooms have also been associated with a wide variety of health benefits, from regulating blood sugar to dropping cholesterol levels. They are also considered adaptogens, meaning that they contain powerful properties that can help naturally restore and balance the body to promote better health.


1. Balances Blood Sugar

Sustaining high levels of sugar in your blood can bring some serious consequences when it comes to your health. Not only can high blood sugar lead to the development of diabetes, but it can also cause side effects like headaches, increased thirst, blurred vision and weight loss.

Long term, diabetes symptoms can become even more serious, ranging from nerve damage to kidney problems.

When consumed as part of a healthy, well-rounded diet, maitake mushrooms may help stabilize blood sugar levels to sidestep these negative symptoms. One animal model conductedby the Department of Food Science and Nutrition at Nishikyushu University’s Faculty of Home Economics in Japan found that administering Grifola frondosa to diabetic rats improved glucose tolerance and blood glucose levels.

Another animal study had similar findings, reporting that the fruit of the maitake mushroom possesses powerful anti-diabetic properties in diabetic mice.

2. May Kill Cancer Cells

In recent years, several promising studies have researched the potential connection between the maitake mushroom and cancer. Although research is still limited to animal models and in vitro studies, maitake grifola may contain powerful cancer-fighting properties that make the fungi a worthy addition to any diet.

One animal model published in the International Journal of Cancershowed that administering an extract derived from the Grifola frondosa to mice helped effectively block tumor growth.

Similarly, a 2013 in vitro study reported that maitake mushroom extract could be useful in suppressing the growth of breast cancer cells.

3. Lowers Cholesterol Levels

Keeping your cholesterol levels in check is absolutely essential when it comes to maintaining a healthy heart. Cholesterol can build up inside the arteries and cause them to harden and narrow, blocking blood flow and forcing your heart to work harder to pump blood throughout the body.

Although more research is needed, some studies suggest that maitake mushrooms could help naturally lower cholesterol levels to keep your heart healthy. An animal model published in theJournal of Oleo Science, for example, found that supplementation with maitake mushrooms was effective in reducing cholesterol levels in mice.

4. Boosts Immune Function

The health of your immune system is vital to overall health. It acts as a natural defense system for your body and helps fights off foreign invaders to protect your body against injury and infection.

Maitake contains beta glucan, a polysaccharide found in fungi that supports healthy immune function, among other health benefits.

Adding a serving or two of Grifola frondosa to your diet may help boost your immune system to ward off disease. An in vitro study published in theAnnals of Translational Medicine concluded that maitake grifola mushrooms were effective in stimulating an immune response and were even stronger when paired with shiitake mushrooms.

In fact, the researchers out of theUniversity of Louisville’sDepartment of Pathology concluded, “Short-term oral application of natural immunomodulating glucans from Maitake and Shiitake mushrooms strongly stimulated both the cellular and humoral branch of immune reactions.”

5. Promotes Fertility

Polycystic ovarian syndrome, also known as PCOS, is a condition caused by an overproduction of male hormones by the ovaries, resulting in small cysts on the ovaries and symptoms like acne, weight gain and infertility.

Some research suggests that maitake mushrooms may be therapeutic against PCOS and could help combat common issues like infertility. A 2010 study conducted at the J.T. Chen Clinic’s Department of Gynecology in Tokyo, for example, found that maitake extract was able to induce ovulation for 77 percent of participants with PCOS and was nearly as effective as some of the conventional medications used for treatment.

6. Reduces Blood Pressure

High blood pressure is an incredibly common health condition that is estimated to affect a whopping 34 percent of U.S. adults. It occurs when the force of the blood through the arteries is too high, placing excess strain on the heart muscle and causing it to weaken.

Regularly consuming maitake can help reduce blood pressure to prevent high blood pressure symptoms. One animal model published in theInternational Journal of Medical Sciences found that giving rats an extract of Grifola frondosa could lessen age-related hypertension.

Another animal study out of theDepartment of Food Chemistry atTohoku University in Japan had similar findings, finding that feeding rats maitake mushroom for eight weeks lowered blood pressure as well as levels of triglycerides and cholesterol.

The Mushroom that Benefits Blood Sugar, Cholesterol, Immunity & More (2)

Nutrition Facts

Maitake mushrooms are low in calories but contain a small chunk of protein and fiber, plus B vitamins, such as niacin and riboflavin, and beneficial beta glucan, which has immune-boosting effects.

One cup (about 70 grams) of maitake mushrooms contains approximately:

  • 22 calories
  • 4.9 grams carbohydrates
  • 1.4 grams protein
  • 0.1 gram fat
  • 1.9 grams dietary fiber
  • 4.6 milligrams niacin (23 percent DV)
  • 0.2 milligram riboflavin (10 percent DV)
  • 0.2 milligramcopper (9 percent DV)
  • 0.1 milligram thiamine (7 percent DV)
  • 20.3 micrograms folate (5 percent DV)
  • 51.8 milligrams phosphorus (5 percent DV)
  • 143 milligrams potassium (4 percent DV)

In addition to the nutrients listed above, maitake grifola also contains a small amount of zinc, manganese, selenium, pantothenic acid and vitamin B6.


Maitake vs. Other Mushrooms

Much like maitake, reishi mushrooms and shiitake mushrooms are both revered for their potent health-promoting properties. The reishi mushroom, for example, has shown to be therapeutic against cancer and reduce cardiovascular risk factors, such as high blood pressure and increased cholesterol levels.

Shiitake mushrooms, on the other hand, are thought to fight obesity, support immune function and reduce inflammation.

While reishi mushrooms are mostly found in supplement form, both shiitake and maitake are more commonly used in cooking.

Like other mushroom varieties, such as the portobello mushroom, shiitake mushrooms are also a popular meat substitute for their woodsy flavor and meat-like texture. Both maitake and shiitake mushrooms are often added to burgers, stir-fries, soups and pasta dishes.

Nutritionally speaking, shiitake and maitake are pretty similar. Gram for gram, maitakes are lower in calories and higher in protein, fiber, niacin and riboflavin than shiitake mushrooms.

Shiitake, however, contains a higher amount of copper, selenium and pantothenic acid. Both can be added to a balanced, well-rounded diet to take advantage of their respective nutrition profiles.

How to Use

Grifola frondosa is in season between late August and early November and can be found growing at the base of oak, maple and elm trees. Be sure to select those that are young and firm, and always wash them off thoroughly before consuming.

If you’re not as well-versed in mushroom hunting and are wondering where to find maitake, you may need to venture beyond your local grocery store. Specialty stores or online retailers are your best bets for getting your hands on these tasty mushrooms. You can also find maitake D fraction extract in supplement form from many health food stores and pharmacies.

Of course, be sure to check the label carefully to prevent confusion with Grifola frondosa lookalikes, such asLaetiporus sulphureus, also known as chicken of the woods mushroom. Although these two mushrooms share similarities in their names and appearance, there are plenty of differences in taste and texture.

The maitake flavor is often described as strong and earthy. These mushrooms can be enjoyed in many different ways and can be added to everything from pasta dishes to noodle bowls and burgers.

Some people also enjoy roasting them until crisp with just a hint of grass-fed butter and a dash of seasoning for a simple yet delicious side dish. Like other mushroom varieties, such as cremini mushrooms, maitake mushrooms can also be stuffed, sautéd or even steeped into a tea.

There are plenty of ways to start enjoying the health benefits of these delicious mushrooms. They can be swapped into just about any recipe that calls for mushrooms or incorporated into main courses and side dishes alike.

Check out these Grifola frondosarecipes to get started:

Risks and Side Effects

For most people, maitake mushrooms can be safely enjoyed with minimal risk of side effects. However, some people have reported allergic reactions after consuming maitake mushrooms.

If you notice any food allergy symptoms, such as hives, swelling or redness, after eating Grifola frondosa, discontinue use immediately, and consult with your doctor.

If you are taking medicine to lower your blood glucose, blood pressure or cholesterol levels, it’s best to discuss with your health care provider before taking maitake mushrooms to avoid interactions or side effects.

Additionally, if you are pregnant or breastfeeding, it’s best to stay on the safe side and limit your intake to prevent adverse symptoms, as the effects of maitake mushrooms (especially maitake D fraction drops) have not yet been studied in these populations.


  • Grifola frondosais a type of edible fungus commonly grown in China, Japan and North America.
  • Known for their medicinal properties, maitake mushrooms have been shown to help balance blood glucose, boost immune function, work as a treatment for high cholesterol levels, reduce blood pressure and promote fertility. They may also have an anti-cancer effect.
  • Grifola frondosa is also low in calories but contains a good amount of protein, fiber, niacin and riboflavin. Maitake taste is described as strong and earthy.
  • You can find maitakes at a local grocery store. They can be stuffed, sautéd or roasted, and there are plenty of maitake recipe options available offering unique ways to use this nutritious mushroom.

Related: Is Mushroom Coffee Even Better than Regular Coffee?

The Mushroom that Benefits Blood Sugar, Cholesterol, Immunity & More (2024)
Top Articles
Latest Posts
Article information

Author: Msgr. Refugio Daniel

Last Updated:

Views: 6293

Rating: 4.3 / 5 (54 voted)

Reviews: 85% of readers found this page helpful

Author information

Name: Msgr. Refugio Daniel

Birthday: 1999-09-15

Address: 8416 Beatty Center, Derekfort, VA 72092-0500

Phone: +6838967160603

Job: Mining Executive

Hobby: Woodworking, Knitting, Fishing, Coffee roasting, Kayaking, Horseback riding, Kite flying

Introduction: My name is Msgr. Refugio Daniel, I am a fine, precious, encouraging, calm, glamorous, vivacious, friendly person who loves writing and wants to share my knowledge and understanding with you.